Аннотация
Проведён сравнительный анализ возрастной динамики морфометрических показателей нейронов дорсального наружного коленчатого тела (НКТд) кошки (Felis catus) на срезах, изготовленных во фронтальной и сагиттальной плоскостях. Исследована возрастная динамика площади, округлости и ориентации сомы геникулятных нейронов, иммунопозитивных к нефосфорилированным доменам тяжёлых нейрофиламентов (антитела SMI-32). Анализ проведён на животных в возрасте 0, 4, 10, 14, 21, 28, 34, 62 и 123 дней и на взрослых животных. Между пулами данных, полученными с использованием фронтальных и сагиттальных срезов, выявлены достоверные отличия: 1) площадь сомы на фронтальных срезах меньше, чем на сагиттальных срезах во всех возрастных группах, с возрастом разница в площади сомы увеличивается; 2) сома нейронов ориентирована под разными углами в двух плоскостях резки, с возрастом происходит достоверное изменение ориентации сомы на сагиттальных, но не фронтальных срезах. Было предположено, что различия в площади сомы являются следствием пространственной организации SMI-32(+) клеток в пределах НКТд, ввиду чего резка в сагиттальной плоскости, в отличие от фронтальной, проходила через длинную ось их сомы. В свою очередь, возрастные изменения в ориентации сомы могут отражать внутреннюю перестройку ретинотопической организации НКТд с возрастом.
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