Abstract
The study was aimed to experimentally verify our hypothesis that in elderly people an endogenous functional mechanism develops during late ontogeny to protect muscle effectors of the cardiovascular system (CVS) against negative effects of sympathetic nervous system overactivity through partial replacement of its neurotransmitter norepinephrine by humoral catecholamines. Experiments were carried out using our method of arterial piezopulsometry, which allows evaluation of cardiac hemodynamic parameters, and a spectral power of VmaxPP and TNN oscillations in arterial blood pressure pulse waves caused by regulatory effects of the autonomic nervous and endocrine systems. Such a replacement is assumed to be crucial for boosting the metabolic resistance of the CVS in elderly people to an age-related increase in oxygen deficiency, as well as for reducing the incidence of tachyarrhythmia, stenocardia and other cardiac pathological conditions under the influence of psychoemotional and physical stressors.